|本期目录/Table of Contents|

[1]林清华,张楚富,刘焱文.牛至挥发油对小鼠特异性免疫功能的影响[J].应用与环境生物学报,1997,3(04):389-391.
 Lin Qinghua,Zhang Chufu,Liu Yanwen.EFFECTS OF VOLATILE OIL OF ORIGANUM VULGARE L.ON SPECIFIC IMMUNOLOGICAL FUNCTIONS IN MICE[J].Chinese Journal of Applied & Environmental Biology,1997,3(04):389-391.
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牛至挥发油对小鼠特异性免疫功能的影响()
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《应用与环境生物学报》[ISSN:1006-687X/CN:51-1482/Q]

卷:
3卷
期数:
1997年04期
页码:
389-391
栏目:
论文
出版日期:
1997-11-25

文章信息/Info

Title:
EFFECTS OF VOLATILE OIL OF ORIGANUM VULGARE L.ON SPECIFIC IMMUNOLOGICAL FUNCTIONS IN MICE
作者:
林清华1 张楚富1 刘焱文2
1. 武汉大学生命科学学院 武汉430072;
2. 湖北中医学院 武汉430061
Author(s):
Lin Qinghua Zhang Chufu Liu Yanwen
1. School of Life Science, Wuhan University, Wuhan 430072;
2. Hubei College of Traditional Chinese Medicine, Wuhan 430061
关键词:
牛至挥发油细胞免疫体液免疫溶血素迟发型超敏反应
Keywords:
volatile oil of Origanum vulgare L.cell-mediated immunityhumoral immunityhemolysindelayed type hypersensitivity
摘要:
牛至(止痢草,土香薷,Origanum vulgare L.)主治中署、感冒、急性胃肠炎、黄疽等症[1],其挥发油(The valatile oil of Origanwrs vulgare L.,简称V0)对30多株致肠炎常见菌均有不同程度的杀菌和抑菌作用[2],并能显著提高小鼠腹腔巨噬细胞活性[3].为了进一步阐明该药抗炎作用的免疫机理,我们观察了VO对小鼠特异性细胞免疫和体液免疫功能的影响,现将结果报告如下.
Abstract:
The experimental results showed that volatile oil of Origanum vulgare L.(VO) significantly inhibited skindelayed type hypersensitivity (DTH) of mice induced by Dinitrochlorobenzene (DNCB) and sheep red blood cell(SRBC), and also inhibited the production of hemolysin in serum and SRBC hemolysis mediated by spleen cells atthe same dose of 100 mg·kg-1×7 d ip.The results also indicated it could cause thymus and spleen atrophyin mice at the dose.When the dose of VO was reduced to 50 mg·kg-1·d-1×7 d ip, it significantly increasedthe level of hemolysin in the serum of the mice and SRBC hemolysis mediated by spleen cells.VO couldremarkably inhibited DTH in mice induced by DNCB and SRBC at the dose.It suggested that VO could inhibit specificCell-mediated immunity and had different effects on specific humoral immunity with different doses.

参考文献/References:

[1] 《全国中草药汇编》编写组.全国中草药汇编(上册).北京:人民卫生出版社,1976
[2] 林清华,刘波,徐有为等.牛至挥发油对肠炎常见菌的体外抗菌作用.应用与环境生物学报.19973(1):76~78
[3] 林清华,汤汉文,王礼德.牛至挥发油对小鼠腹腔巨噬细胞活性及免疫器官重量的影响.基础医学与临床.1990,10(1):49~51
[4] 林清华,付晓琴,冯敏燕等.羧甲基变性半纤维素对小鼠某些免疫功能的影响.生理科学.1987,7(5):291~293
[5] 邓文龙,刘家玉,聂仁吉.昆明山海棠的药理作用研究Ⅱ,对免疫功能的影响.中草药.1981,1200):26~30
[6] 李卓娅,冯新为.氰味咪胍对小鼠抗羊红细胞的细胞免疫与体液免疫的影响.上海免疫学杂志.1988.8(4):254~257
[7] 林飞卿,余传霖,何球藻主编.医学基础免疫学.上海:上海医科大学出版社.1992

相似文献/References:

[1]林清华,刘波,徐有为,等.牛至挥发油对肠炎常见菌的体外抗菌作用[J].应用与环境生物学报,1997,3(01):76.
 Lin Qinghua,Liu Bo,Xu Youwei,et al.ANTIBIOTIC EFFECT IN VITRO OF VOLATILE OIL OF ORIGANUM VULGARE L. ON ENTERITIS-CAUSING BACTERIA[J].Chinese Journal of Applied & Environmental Biology,1997,3(04):76.

备注/Memo

备注/Memo:
收稿日期:1995-8-25;接受日期:1996-10-18。
更新日期/Last Update: 1900-01-01